The leaves of the kratom tree contain psychoactive compounds, particularly alkaloids such as mitragynine and 7-hydroxymitragynine. These alkaloids have opioid-like effects and can interact with opioid receptors in the brain, leading to pain relief, sedation, and euphoria. Kratom has been traditionally used in its native regions for its stimulant and analgesic properties.

Kratom leaves are typically dried and powdered, brewed into tea, or consumed in capsule form. The effects of kratom can vary depending on the strain and dosage used. Lower doses tend to produce stimulant effects, such as increased energy, sociability, and focus, while higher doses can have more sedating and pain-relieving effects.